How To Take Lamictal (Lamotrigine)

LAMICTAL (lamotrigine)

LAMICTAL (lamotrigine) is formally classified as an anticonvulsant drug.  However, it has been used for many years for migraines and pain.  It is also effective for treating bipolar depression.

WARNING: STOP THE MEDICATION IMMEDIATELY IF A RASH APPEARS.

To minimize the possibility of rash:

  • Start at a low dose
  • Increase the medication very slowly

If the medication is discontinued due to rash, it may be tried again.  However, the rash must be completely gone.  The starting dose needs to be even lower, and raised more slowly.   If the rash recurs, stop the medication immediately.

Lamictal comes in scored tablets of 25, 100, 150, and 200mg. It is most cost effective to buy the larger sizes and cut them in half.

Dosing Guidelines
Week Morning dose Bedtime dose
1 12.5mg
2 12.5mg 12.5mg
3 12.5mg 25mg
4 25mg 50mg
5 50mg 50mg
6 50mg 75mg
7 75mg 75mg
8 75mg 100mg
9 100mg 100mg

The dose may need to be increased to a total of 250-400mg.

SIDE EFFECTS

If significant side effects occur (e.g. dizziness on 25mg), the dose may be reduced even further. 

To decrease side effects (especially risk of rash) take each dose for 2 weeks.

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