Integrative Health Consultant and Educator
Integrative Health Consultant and Educator

Desoxyn vs. Adderall and Dexedrine

Question: How is Desoxyn different from Adderall and Dexedrine?
Answer: There is a lot of literature to support the fact that abuse liability is related to reuptake blockade and/or increased release of dopamine in the nucleus accumbens. The best resource is ADD Treatment with Stimulants, by Solanto, et al, 2001.
Recent reports by 5 different agencies (including DEA and OIG) that monitor substance abuse have found that Methamphetamine (Desoxyn) is by far the most abused stimulant. All this data is available through the Freedom of Information Act at each agency.
I have been prescribing Desoxyn for over 30 years. It has been available since 1941. It is clearly the most likely to be abused. Clinically it is sometimes the best tolerated. The most likely explanation for this is a reduced relative effect on Norepinephrine.

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